MRD testing leverages sensitive technologies such as next-generation sequencing, digital droplet PCR, and flow cytometry to screen residual blood, bone marrow, or cerebrospinal fluid for trace amounts of tumor biomarkers that may not be visible on standard imaging scans. MRD assays provide earlier and more accurate information about treatment response and risks of disease relapse compared to conventional monitoring methods. They enable timely optimization of care through modification of therapeutic strategies or closer patient surveillance.
The global minimal residual disease testing market is estimated to be valued at US$ 4.97 Bn in 2024 and is expected to exhibit a CAGR of 11% over the forecast period 2024 to 2031.
Key Takeaways
Key players operating in the minimum residual disease testing market are Bio-Rad Laboratories, Inc., F. Hoffmann-La Roche Ltd, Guardant Health, Inc., Adaptive Biotechnologies, Invitae Corporation, ASURAGEN, INC., Invivoscribe, Inc., Laboratory Corporation of America Holdings, Natera, Inc., Sysmex Inostics, Inc., Amgen Inc., FOUNDATION MEDICINE, INC., Sebia, and Myriad Genetics, Inc.
Growing demand for MRD testing stems from increasing adoption in clinical trials evaluating new cancer drugs as a surrogate endpoint for outcomes. MRD assays potentially allow faster assessment of treatment efficacy, shortening development timelines and expediting regulatory approvals.
Globally, suppliers are engaging in partnerships, collaborations, and geographic expansions to address the worldwide need for sensitive, scalable MRD testing platforms across diverse hematologic and solid tumor types. Centralized laboratories and point-of-care technologies aim to deliver MRD testing accessibility everywhere.
Market Drivers
The primary market driver is the rising clinical utility of MRD screening for treatment guidance and monitoring disease recurrence risk. MRD results complement conventional staging and imaging to personalize therapy duration and intensity. Also fueling adoption are the improved cure rates and survival outcomes demonstrated by MRD-guided clinical trials in blood cancers. This is elevating MRD to a standard of care indicator and strengthening the value proposition for related products.
The current geopolitical situation is significantly impacting the growth of the minimal residual disease testing market. The ongoing Russia-Ukraine conflict and rising political tensions between major economies like the US and China are disrupting global supply chains and increasing costs. This is hindering easy access to critical medical equipment, reagents, and components used for minimal residual disease testing. Additionally, certain regions experiencing geopolitical instability and conflicts have seen reduced healthcare spending that is negatively impacting the adoption of modern diagnostic technologies like minimal residual disease testing.
To sustain long-term growth, companies in the Minimal Residual Disease Testing Market Size need to focus on diversifying their supplier networks and establishing local manufacturing facilities in different geographies. This will help mitigate over-dependence on key regions for sourcing. Co-development partnerships with regional pharma/biotech firms can aid local product development and registration to cater to the needs of specific markets. Market players must also explore viable funding options to support healthcare infrastructure development and diagnostic access programs in emerging nations facing socio-economic challenges. This will open up new growth avenues despite faced geopolitical headwinds.
In terms of value, North America holds the largest share of the minimal residual disease testing market and is estimated to surpass US$ 2 Bn by 2031 driven by robust access to advanced cancer care, widespread health insurance coverage, and presence of leading market.
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