Cephalosporin: Powerful antibiotics against bacterial infections

Cephalosporin Drugs exert their antibacterial effect by inhibiting the transpeptidation and transglycosylation reactions of the peptidoglycan layer synthesis in bacterial cell walls. Specifically, they bind to and inhibit penicillin-binding proteins (PBPs) responsible for the final stages of peptidoglycan synthesis. By interfering with cell wall construction, cephalosporins disrupt the structural integrity and osmotic equilibrium of bacterial cells, ultimately leading to their death.

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