The primary concern when combining Duratia with herbal supplements is the potential for harmful interactions. Because Duratia increases serotonin levels, taking it with certain herbal supplements that also affect serotonin can lead to a dangerous condition known as serotonin syndrome. This occurs when there is an excess of serotonin in the brain, causing symptoms such as agitation, confusion, rapid heart rate, muscle rigidity, and, in severe cases, seizures or death.
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