Beyond Single Columns: How Multi-Column Chromatography Advances Biomolecule Purification

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The Chromatography Columns Market is growing at a CAGR of 5.80%, driven by advancements like multi-column chromatography and automation

The Chromatography Columns Market is witnessing significant advancements with the emergence of multi-column chromatography systems. Multi-column chromatography represents a cutting-edge approach to chromatographic separations, allowing for enhanced efficiency, throughput, and purification yields. In multi-column chromatography, multiple chromatography columns are interconnected in parallel or series configurations, enabling simultaneous or sequential processing of samples. This innovative technology offers several advantages over traditional single-column chromatography, including reduced processing times, higher sample throughput, and improved purification capabilities. By leveraging the principles of parallel processing and column switching, multi-column chromatography systems enable researchers and biopharmaceutical manufacturers to achieve higher productivity and scalability in downstream purification processes, driving growth within the Chromatography Columns Market.

The Chromatography Columns Market Size was valued at USD 12.5 billion in 2022 and is projected to grow from USD 13.22 Billion in 2023 to USD 18.54 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 5.80% during the forecast period (2023 – 2030).

Market Segmentation:

The market for chromatography columns is segmented based on column type, chromatography type, application, and end-user.

  1. Column Type:
    • Pre-packed chromatography columns
    • Automated chromatography columns
    • Normal phase chromatography columns
  2. Chromatography Type:
    • Affinity chromatography
    • Ion-exchange chromatography
    • Size exclusion chromatography
    • Gas chromatography
    • Others
  3. Application:
    • Sample preparation
    • Anion and cation exchange
    • Protein purification
    • Desalting
    • Resin screening
    • Others
  4. End-User:
    • Food & beverage manufacturers
    • Pharmaceutical biotechnology companies
    • Research institutes
    • Others

Regional Insight:

The market is analyzed across different regions:

  1. North America:
    • Largest market share
    • Presence of well-known chromatography column developers such as Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., and Thermo Fisher Scientific Inc.
    • Significant R&D spending and focus on launching new products enhance market growth.
  2. Europe:
    • Growing market size
    • Presence of renowned players such as Biotage, KNAUER WissenschaftlicheGeräte GmbH, and Merck KGaA
    • Emphasis on manufacturing new and advanced products, seeking regulatory approvals to enhance market presence.
  3. Asia-Pacific:
    • Emerging market with well-established healthcare infrastructure in countries like India and Japan
    • Presence of affluent developers such as Shimadzu Corporation and Daicel Corporation
    • Government support for healthcare infrastructure improvement
    • Market growth expected due to increasing demand and advancements in the region.

Amidst the evolving landscape of chromatography technology, automated column chromatography systems are revolutionizing laboratory workflows and process efficiency within the Chromatography Columns Market. Automated column chromatography streamlines chromatographic separations by integrating advanced automation and control features into chromatography systems. These systems automate key steps in the chromatography process, including sample loading, column equilibration, gradient elution, and fraction collection, minimizing manual intervention and reducing processing times. By eliminating tedious manual tasks and optimizing chromatography parameters, automated column chromatography systems enhance reproducibility, accuracy, and productivity in laboratory settings. With a growing demand for high-throughput and cost-effective purification solutions, automated column chromatography systems are poised to drive innovation and growth in the Chromatography Columns Market, offering researchers and biopharmaceutical manufacturers efficient tools for biomolecule purification and analysis.

Reputed Firms

Agilent Technologies, Inc. (US), Daicel Corporation (Japan), Shimadzu Corporation (Kyoto), Merck KGaA (Germany), Thermo Fisher Scientific Inc. (US), Biotage (Sweden), Waters (US), KNAUER WissenschaftlicheGeräte GmbH (Germany), PerkinElmer Inc. (US), Bio-Rad Laboratories Inc. (US) are the prominent chromatography column companies, outlined in the MRFR review study.

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